The 1988 chronic fatigue syndrome (CFS) working case definition (Holmes, et al)

http://www.cdc.gov/ncidod/diseases/cfs/defined/

The 1988 chronic fatigue syndrome (CFS) working case definition (Holmes, et al) did not effectively distinguish CFS from other types of unexplained fatigue. For this reason, it was decided during a 1993 meeting of CFS investigators to develop a logical revision of that definition.

	Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution. This publication addresses problems in applying the 1994 CFS Research Case Definition and recommends an approach to guide systematic reproducible application of the case definition in research studies. The article should also be helpful to health care professionals who care for persons with CFS.
	Rational for Revising the CFS Case Definition
	The Revised Case Definition (abridged version)
	Complete Text of Revised Case Definition as Published
	A brief explanation of how CFS patients are evaluated by a physician is available with visual graphics or as text only
	Screening Tests for Detecting Common Exclusionary Conditions