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http://mecvswetenschap.wordpress.com/2009/08/
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Inspanning-responsieve genen bij CVS
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http://www.hetalternatief.org/Light%20Inspanning%20Pijn%202009%20574.htm
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Dr. Alan Light en kollega's van de universiteit
van Utah hebben aangetoond dat de genenxepressie van ME(CVS)-patiënten
na een kleine inspanning duidelijk afwijkt van die van gezonde mensen.
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http://mecvswetenschap.wordpress.com/ |
Bij een studie van 2 gen-gen associatie-netwerken bij CVS
(Integratie
van klinische, genetische en proteïne-gegevens bij CVS)
bleek HDAC7A in beide voor te komen. Gen-expressie van HDAC7A
(een gen dat codeert voor een histoon-deacetylase (enzyme);
histoon-acetylatie/-deacetylatie verandert de struktuur van
chromosomen en beïnvloedt de toegang van transcriptie-factoren tot
DNA) bleek tevens gecorreleerd met onverklaarde vermoeidheid in een
andere studie |
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http://www.cinner.com/2005/07/26/
genetische-afwijking-gevonden-bij-me-patienten/
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In een artikel
in het gerenommeerde tijdschrift New Scientist maakten Britse onderzoekers
afgelopen zaterdag melding van de vondst van genetische verschillen
in witte bloedcellen tussen ME-patiënten en gezonde mensen [1]. Hiermee
menen zij het bewijs te hebben geleverd van de biologische oorsprong
van ME
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http://www.planet.nl/planet/sho
id=75098/contentid=607974/sc=f55081#
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Vermoeidheidssyndroom
mogelijk toch ziekte
Bij patiënten met het chronisch
vermoeidheidssyndroom (CVS) zijn duidelijke lichamelijke verschillen
gevonden vergeleken met gezonde mensen.
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http://www.immunesupport.com/library/
showarticle.cfm?id=8161&T=CFIDS_FM&B1=EM071807C
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Gene expression correlates of Postinfective Fatigue Syndrome after infectious
mononucleosis
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https://listserv.surfnet.nl/scripts/WA.EXE?S2=me-net&q=&I=1&f=me-net&s=Gen-nieuws+uit+Glasgow
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Gen nieuws
uit Glasgow
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http://www.biomedcentral.com/1755-8794/2/38
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A Gene Signature for Post-Infectious Chronic Fatigue Syndrome
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http://www.ncbi.nlm.nih.gov/pubmed/19647494
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Moderate Exercise Increases Expression for Sensory, Adrenergic, and
Immune Genes in Chronic Fatigue Syndrome Patients But Not in Normal
Subjects.
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http://www.cfsrf.com/pdf/Newsletter-10.pdf
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Gene expression
describes the behaviour of genes when when attacked by an infection
of other disturbance
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http://www.meresearch.org.uk/research/
sponsored/genesig.html
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the pilot
data obtained by Dr Gow's team have suggested alterations to genes controlling
the metabolism of prostaglandin and those regulation-specific immune
cells. This is interesting work which deserves to be supported into
its mature phase when a specific "gene signature" for particular proteins
may be revealed.
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http://www.bsn.org.uk/view_all.php?id=11707
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Dr. Jonathan Kerr, principal investigator, St. George's Medical School"We’ve
shown that several hundred genes are very, very different between patients
and controls and we now must make sure that these are specific differences
to this disease and after that we can use that information to design
new treatments.”
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http://www.cfsrf.com/pdf/CFS-gene-1a.pdf
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ORIGINAL ARTICLE : Gene expression in peripheral blood mononuclear cells
from patients with chronic fatigue syndrome
N Kaushik, D Fear, S C M Richards, C R McDermott, E F Nuwaysir, P Kellam,
T J Harrison, R J Wilkinson, D A J Tyrrell, S T Holgate, J R Kerr
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http://www.scottish.parliament.uk/business/
officialReports/meetingsParliament/or-05/sor0609-02.htm
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The Scottish
Conservatives are pleased to make our time in the Parliament available
to members to debate the Kerr report and the state of the national health
service in Scotland. It is a matter of regret that the Scottish Executive
refused to do so in its time prior to the recess, given the importance
of the subject.
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http://www.me-cvs.nl/index.php?pageid=7773
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Gray matter
volume reduction in the chronic fatigue syndrome
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http://www.cfids-cab.org/cfs-inform/Cytokines/kerr.tyrrell03.pdf
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Cytokines in Parvovirus B19 Infection As an Aid to Understanding Chronic
Fatigue Syndrome
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http://listserv.nodak.edu/cgi-bin/wa.exe?A2=ind0508A&L=co-cure&P=R2914
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concludes
that patients with ME/ICD-CFS have reproducible alterations in gene
regulation and that sixteen genes have an expression profile associated
with the disorder that can be grouped according to immune, neuronal,
mitochondrial and other functions.
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http://www.timesonline.co.uk/article/0,,2-1702267,00.html
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The analysis of 9,522 genes identified 35 that appeared
to show differences, and a more precise examination of these revealed
significant and genuine changes in the way that 16 of the genes were
expressed in the CFS group.
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http://www.newscientist.com/channel/
health/mg18725093.700
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Differences
in gene expression have been found in the immune cells of people with
the disease, a discovery that could lead to a blood test for the disorder
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http://www.25megroup.org/Newsletter/
Issue%2018/CFSRF%2018.htm
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When a person is attacked by an infection some genes
become very active while others shut down. The overactive genes
produce chemicals, which cause the symptoms of the illness. Scientists
carrying out this study will be examining the overactive genes to identify
the chemicals that they are producing. These chemicals may then
be targeted by existing or novel drugs
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http://thestar.com.my/health/story.asp?file=/
2005/7/27/health/11573143&sec=health
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Kerr’s team found that a group of genes in the white blood cells of
CFS sufferers were up to four times more active than those without the
affliction while one was less active.“The involvement of such genes
does seem to fit with the fact that these patients lack energy and suffer
from fatigue,”
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http://www.immunesupport.com/library/
showarticle.cfm/id/6593
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Scientists
believe they have pinpointed biological markers of chronic fatigue syndrome
which could help develop a test and treatment for the condition.
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http://www.meactionuk.org.uk/
Evidence-based_Psychiatry.htm
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In as yet
unpublished work, bona fide research has indicated that in those with
ME/ICD-CFS there are more gene abnormalities present than are found
in cancer sufferers.
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http://www.ncf-net.org/forum/GeneProfiling.htm
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The Centers for Disease Control recently published the results of their
study of CFS patients in work titled "Utility of the blood for gene
expression profiling and biomarker discovery in chronic fatigue syndrome"
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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=
PubMed&list_uids=8148439&dopt=Abstract
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Studies on
enterovirus in patients with chronic fatigue syndrome.
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http://www.meresearch.org.uk/research/
sponsored/genesig.html
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Gene Research: A Scientific 'Signature' for ME/CFS?
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